JASM 2026 :: Programme

13:30-14:30	Registration
14:30-14:45	Welcome Elda Perlino Assessore al Clima, alla Transizione Ecologica e all'Ambiente del Comune di Bari Grazia Paola Nicchia Direttrice del Dipartimento di Bioscienze, Biotecnologie e Ambiente, Università degli Studi di Bari Aldo Moro
14:45-15:30	Keynote Lecture Introduced by Gabriella Minchiotti Alfonso Martinez Arias (ICREA, Barcelona, Spain) Modeling early development with mouse and human gastruloids
Session 1: Cell Plasticity in Development and Disease Chairs: Gabriella Minchiotti, Thomas Vaccari
15:30-15:45	Filomena Amoroso (CNR, Naples) Stem cell-based embryo models uncover mitochondrial SIRT3 as a regulator of cell fate and embryonic patterning
15:45-16:00	Mariano Stornaiuolo (University of Naples Federico II) Sperm‑derived lipids as early remodeling signals in preimplantation embryo development and metabolism
16:00-16:15	Wanda Lattanzi (Università Cattolica del Sacro Cuore, Rome) Decoding cellular crosstalk in the cranial suture niche to guide targeted therapies for craniosynostosis
16:15-16:45	Coffee break
Session 1 (continued): Cell Plasticity in Development and Disease Chairs: Nicoletta Guaragnella, Massimo Bonora
16:45-17:00	Moise Di Sante (University of Pavia) Mapping integrative cell-cycle and structural dynamics in human 3D systems from regenerative screening in cardiac organoids to morphogenetic disease modeling in gastruloids
17:00-17:15	Matteo Sorge (University of Turin) Human cardiac organoids reveal a functional role of the mechanosensing chaperone Melusin in cardiogenesis
17:15-17:30	Olimpia Iacolare (CNR, Naples) Tbx1 coordinates focal adhesion dynamics and non-canonical Wnt/PCP signaling to regulate cardiac morphogenesis
17:30-17:45	Diletta Capobianco (University of Bari) Intercellular PTBP1 trafficking via tunneling nanotubes and extracellular vesicles regulates human neural stem cell fate
17:45-18:00	Mario De Gregorio (University of Turin) Proteomic profiling of the SKT/KIAA1217 postsynaptic complex reveals a convergent molecular hub linking synaptic development to neurological disease risk
18:00-18:15	Carmela Gagliarde (Sapienza University of Rome) Mechanistic insights into the dysfunctional impact of micro/nanoplastics (MNPs) on human gut health
20:00	Light dinner at "Il priscio" Bari drinks and food

Session 2: Cell Plasticity in Development and Disease Chairs: Anna Maria Porcelli, Annalisa Fico
9:00-9:15	Evelyn Mazzarelli (Humanitas University, Milan) Twist1-driven Epithelial-to-Mesenchymal Transition as a dysfunctional plasticity program in acute intestinal injury
9:15-9:30	Anna Martina Battaglia (Magna Graecia University of Catanzaro) A feed-forward tumour-neuron circuit couples ferroptotic stress to neurotropic plasticity in oral cancer
9:30-9:45	Anna Alessia Saponaro (University of Foggia) Three-dimensional tumor spheres reveal architecture-dependent miRNome changes associated with stemness across cancer models
9:45-10:00	Francesca Fracasso (University of Bari) Extracellular acidosis promotes vasculogenic mimicry in pancreatic cancer stem cells by increasing NHE1 activity and intracellular Ca²⁺
10:00-10:15	Martina Mugnano (IGB, Naples) Label-free holotomography and machine learning for biophysical profiling of pancreatic cancer and stromal cells
10:15-10:30	Francesco Farris (IFOM-ETS, Milan) ECM architecture is governed by BACE2-mediated collagen proteostasis
10:30-10:45	Gianvito Donvito (Bari) ELIXIR-IT: the Italian research infrastructure for big data in life sciences
10:45-11:15	Coffee break
11:15-12:00	Keynote Lecture Introduced by Anna Maria Porcelli Silvia Fre (Institut Curie, Paris, France) Conserved signals dictate symmetry braking and regeneration of multilayered epithelia
12:00-14:00	Lunch break on own
Session 3: Cellular Signaling & Membrane Trafficking Chairs: Sara Sigismund, Mario Chiariello
14:00-14:15	Elena Ziviani (University of Padua) Protective effect of enhanced mitophagy by a potent small molecule inhibitor of USP14
14:15-14:30	Daniela Guarnieri (University of Salerno) Lysosome-confined nanoparticles rewire organelle contact sites to coordinate cellular stress responses
14:30-14:45	Paola Rusmini (University of Milan) TFEB-dependent lysosomal exocytosis links trehalose treatment to neurite outgrowth in neurodegenerative disease models
14:45-15:30	Keynote Lecture Introduced by Sara Sigismund Claudio Joazeiro (University of Heidelberg, Germany) Protein quality control and ubiquitin ligases in health and disease
15:30-17:00	Poster Session and coffee break
Session 3 (continued): Cellular Signaling & Membrane Trafficking Chairs: Simona Paladino, Pier Paolo Di Fiore
17:00-17:15	Giuseppina Amodio (University of Salerno) Synaptojanin-1: a novel regulator of COPII vesicles assembly and ER export
17:15-17:30	Paola Zanfardino (University of Bari) Distinct genetic defects reshape mitochondrial homeostasis and mTOR/AKT signalling in inherited neuropathies
17:30-17:45	Antonio Galeone (CNR-NANOTEC, Lecce) TUSC3 gates BMP4/Dpp secretion through a glycan-mediated ER triage checkpoint
17:45-18:00	Simona Barile (CNR IBIOM, Bari) Impaired mitochondrial calcium homeostasis in iPSC-derived AGC1-deficient neuronal progenitors
18:00-18:15	Gaia Sarcinelli (Humanitas University, Milan) Functional contribution of Epithelial-to-Mesenchymal Plasticity to cancer initiation
18:15-18:30	Maria Antonietta Di Noia (University of Bari) Citrate trafficking supports mitochondrial rewiring during osmoadaptation: premises and prospects
18:30-18:45	Carlo Cosimo Campa (Italian Institute for Genomic Medicine, Turin) Multimodal interrogation of small GTPase conformational changes using fluorogen-activating biosensors
20:30	Social dinner at "Circolo Unione di Bari"

Session 4: Cellular Signaling & Membrane Trafficking Chairs: Simona Polo, Rossella Venditti
9:15-9:30	Francesca Nigrelli (University of Turin) Multilevel regulation of Wnt/β-catenin signalling by p140Cap in breast cancer
9:30-9:45	Chiara Sacchi (IFOM-ETS, Milan) RBM47 modulates epithelial junctional integrity in the intestine through alternative splicing of cytoskeletal proteins
9:45-10:00	Alberico Di Pinto (Sapienza University of Rome) ACP2 promotes lysosomal degradation of ERAP1 to modulate Sonic Hedgehog signaling
10:00-10:15	Eleonora Di Venere (University of Naples Federico II) From centrosome to primary cilium: the emerging role of TRIM8
10:15-10:30	Angela Antonia Rilievo (Vita-Salute San Raffaele University, Milan) Targeting CSF-1R and HMGB1 to reshape the tumor microenvironment in mesothelioma
10:30-11:00	Coffee break
11:00-11:45	Keynote Lecture Introduced by Simona Polo Madelon Maurice (UMC Utrecht, The Netherlands) Cellular plasticity in colorectal cancer: Identity crisis or a matter of self-organization?
11:45-12:00	Prizes for best poster and oral presentation
12:00-12:30	Closing remarks

When preparing your poster please remember that the poster's maximum size is 70 x 100 cm; width x height.

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Poster Session • 19 November • 15:30-17:00

P.1 Antonio Adinolfi (Naples)
CBX6 regulates epigenetic plasticity and cell identity in glioblastoma
P.2 Ilaria Asci (Bari)
A215T disrupts the conformational maturation of all AQP4 isoforms and targets them to ER-associated degradation in megalencephalic leukoencephalopathy with subcortical cysts type 4 (MLC4)
P.3 Rosa Cardone (Bari)
circBFAR increases tumor cell invasion and modulates resistance to gemcitabine-based chemotherapy in pancreatic cancer.
P.4 Mario Chiariello (Siena)
Intraoperative tumor sequencing for personalized loco-regional drug combination therapy against glioblastoma recurrences
P.5 Tommaso Colangelo (Foggia)
Epigenetic control of cancer cell identity: TIMELESS-ZEB1 and TIMELESS-UHRF1 axes link genome maintenance to differentiation and stemness
P.6 Arianna Coppola (Naples)
Investigating IRF2BPL dysfunction and PTC suppression in human pluripotent stem cell models of NEDAMSS
P.7 Cristina D'Aniello (Naples)
Generation and characterization of lung organoids from human pluripotent stem cells to study lung development and disease
P.8 Micaela De Girolamo (Naples)
Glucocorticoid Receptor-Driven Plasticity: linking metabolic reprogramming to ovarian cancer evolution
P.9 Francesco De Leonardis (Bari)
BRCA-1 and BRCA-2 haploinsufficiency drives divergent epithelial-stromal metabolic adaptations in the preneoplastic human breast
P.10 Angela Francesca Dinoi (Lecce)
Precision Medicine Platform for KIF1A-Associated Neurological Disorder (KAND)
P.11 Amir Fardin (Milan)
Glycolipid-lectin driven endocytosis as a therapeutic vulnerability in breast cancer
P.12 Debora Gentile (Catanzaro)
FABP5 connects lipid handling to redox and genomic stability in papillary thyroid carcinoma
P.13 Ombretta Guardiola (Naples)
Unraveling the role of the chemokine receptor CXCR2 in muscle stem cell functional heterogeneity
P.14 Eduardo Ibello (Naples)
Budesonide modulates collective cell behavior in PDAC
P.15 Simone Mas (Palermo)
Budesonide prevents stiffness-induced malignant traits in pancreatic ductal adenocarcinoma cells
P.16 Alessia Nisco (Bari)
Adaptive remodeling of FAD synthase subcellular localization in pancreatic ductal adenocarcinoma cells
P.17 Chiara Paciolla (Bari)
Valeric acid as potential epigenetic modulator of PD-L1 expression in wild-type and BRAF-mutated metastatic melanoma cells
P.18 Alessandro Ruocco (Naples)
Synaptojanin 1 (SYNJ1) overexpression leads to metabolic rewiring in neuronal SH-SY5Y cells
P.19 Daniela Sarnataro (Naples)
Oxidative stress response shapes phenotype-specific TDP-43 proteinopathy across the ALS/FTD spectrum
P.20 Maria Tolomeo (Bari)
Stress-induced RFVT1 upregulation in the neuronal SH-SY5Y cell model: relevance to riboflavin transporter deficiency type 2 (RTD2)
P.21 Thomas Vaccari (Milan)
Early lysosomal dysfunction is associated with altered autophagy-associated cargo trafficking and extracellular DPR accumulation in C9orf72-linked ALS/FTD
P.22 Rossella Venditti (Naples)
TEX2 controls mitochondrial dynamics at ER-mitochondria contact sites
P.23 Angela Primavera (Bari)
Extracellular pH, ion homeostasis and adaptive strategies upon osmostress in a yeast model
P.24 Maria Emanuela Carbone (Naples)
HIPK2 inhibition promotes a MAPK-dependent cytoplasmic accumulation of TDP-43 and the disruption of mitochondria-endoplasmic reticulum contact sites: new insights into ALS molecular pathogenesis

Programme

Programme

Poster Session • 19 November • 15:30-17:00